Complexes:

Name	Rpb41-Rpb42
Species	Sulfolobus solfataricum
Complex ID	500
Molecular description	RNase PH core of the archaeal exosome
Complex ID	Lorentzen, E., Walter, P., Fribourg, S., Evguenieva-Hackenberg, E., Klug, G., Conti, E. The Archaeal Exosome is a Hexameric Ring with Three Catalytic Subunits Nat.Struct.Mol.Biol. v12 pp.575 , 2005 (PubMed)
PDB entry	2br2
Partner	16A
Name	Rpb41-Rpb42-A5RNA
Species	Sulfolobus solfataricum
Complex ID	500
Molecular description	RNase PH core of the archaeal exosome in complex with A5 RNA
Complex ID	Lorentzen, E., Conti, E. Structural Basis of 3' End RNA Recognition and Exoribonucleolytic Cleavage by an Exosome Rnase Ph Core. Mol.Cell.Biol. v20 pp.473, 2005 (PubMed)
PDB entry	2c38
Partner	16A
Name	Rpb41-Rpb42-Rpb4
Species	Sulfolobus solfataricum
Complex ID	500
Molecular description	9-subunit archaeal exosome
Complex ID	Lorentzen, E.,  Dziembowski, A.,  Lindner, D.,  Seraphin, B.,  Conti, E. RNA Channeling by the Archaeal Exosome EMBO Rep. May;8(5):470-6, 2007 (PubMed)
PDB entry	2ja6
Partner	3B, 16A, 18Old picture
Name	Rpb41-Rpb42-Rpb4-RNA	>
Species	Sulfolobus solfataricum
Complex ID	500
Molecular description	9-subunit archaeal exosome in complex with RNA
Complex ID	Lorentzen, E.,  Dziembowski, A.,  Lindner, D.,  Seraphin, B.,  Conti, E. RNA Channeling by the Archaeal Exosome EMBO Rep. May;8(5):470-6, 2007 (PubMed)
PDB entry	2jea
Partner	3B, 16A, 18Old picture
Name	Rrp44/RNA
Species	S. cerevisiae
Complex ID	500
Molecular description	Exosome complex exonuclease
Complex ID	Lorentzen, E., Basquin, J., Tomecki, R., Dziembowski, A. and Conti, E. (2008). Structure of the active subunit of the yeast exosome core, Rrp44: diverse modes of substrate recruitment in the RNase II nuclease family. Mol Cell 29, 717-728. (PubMed)
PDB entry	2vnu
Partner	2B
Name	Rrp44-Rrp41-Rrp45
Species	S. cerevisiae
Complex ID	500
Molecular description	Exosome complex exonuclease
Complex ID	Bonneau F, Basquin J, Ebert J, Lorentzen E, Conti E.The yeast exosome functions as a macromolecular cage to channel RNA substrates for degradation.Cell. 2009 Oct 30;139(3):547-59. (PubMed)
PDB entry	2wp8
Partner	2B
Name	Pol II-RNA inhibitor
Species	S. cerevisiae
Complex ID	145
Molecular description	Complete RNA Polymerase II-RNA inhibitor complex
Complex ID	Kettenberger, H.,  Eisenfuehr, A.,  Brueckner, F.,  Theis, M.,  Famulok, M.,  Cramer, P. Structure of an RNA polymerase II-RNA inhibitor complex elucidates transcription regulation by noncoding RNAs Nat.Struct.Mol.Biol. v13 pp.44-48, 2006 (PubMed)
PDB entry	2b63
Partner	4
Name	Med18/20
Species	S. cerevisiae
Complex ID	139
Molecular description	Mediator head submodule (heterodimer)
Complex ID	Lariviere, L., Geiger, S., Hoeppner, S.,  Rother, S.,  Strasser, K.,  Cramer, P. Structure and TBP binding of the Mediator head subcomplex Med8-Med18-Med20. Nat.Struct.Mol.Biol. v13 pp.895-901, 2006 (PubMed)
PDB entry	2hzm
Partner	4
Name	Med8C/18/20
Species	S. cerevisiae
Complex ID	139
Molecular description	Mediator head submodule (heterotrimer)
Complex ID	Lariviere, L., Geiger, S., Hoeppner, S., Rother, S., Strasser, K.,  Cramer, P. Structure and TBP binding of the Mediator head subcomplex Med8-Med18-Med20. Nat.Struct.Mol.Biol. v13 pp.895-901, 2006 (PubMed)
PDB entry	2hzs
Partner	4
Name	Med7N/31
Species	S. cerevisiae
Complex ID	139
Molecular description	Mediator submodule
Complex ID	Koschubs T, Seizl M, Larivière L, Kurth F, Baumli S, Martin DE, Cramer P. (2009) Identification, structure, and functional requirement of the Mediator submodule Med7N/31. EMBO J. Jan 7;28(1):69-80. (PubMed)
PDB entry	3fbi
Partner	4
Name	Tau60-Tau91
Species	S. cerevisiae
Complex ID	001
Molecular description	Subcomplex of yeast transcription factor IIIC
Complex ID	Mylona, A.,  Fernandez-Tornero, C.,  Legrand, P.,  Haupt, M.,  Sentenac, A.,  Acker, J.,  Muller, C.W. Structure of the Tau60/Deltatau91 Subcomplex of Yeast Transcription Factor IIIC: Insights Into Preinitiation Complex Assembly Molecular Cell v24 pp.221, 2006 (PubMed)
PDB entry	2j04
Partner	16B
Name	MetRS-Arc1p
Species	S. cerevisiae
Complex ID	243
Molecular description	Binary subcomplex of yeast aminoacyl-tRNA synthase
Complex ID	Simader, H.,  Hothorn, M.,  Kohler, C.,  Basquin, J.,  Simos, G.,  Suck, D. Structural basis of yeast aminoacyl-tRNA synthetase complex formation revealed by crystal structures of two binary sub-complexes. Nucleic Acids Res. v34 pp.3968-3979 , 2006 (PubMed)
PDB entry	2hsn
Partner	16A
Name	GluRS-Arc1p
Species	S. cerevisiae
Complex ID	243
Molecular description	Binary subcomplex of yeast aminoacyl-tRNA synthase
Complex ID	Simader, H.,  Hothorn, M.,  Kohler, C.,  Basquin, J.,  Simos, G.,  Suck, D. Structural basis of yeast aminoacyl-tRNA synthetase complex formation revealed by crystal structures of two binary sub-complexes. Nucleic Acids Res. v34 pp.3968-3979 , 2006 (PubMed)
PDB entry	2hrk
Partner	16A
Name	INCEP/Survivin/Borealin
Species	Homo sapiens
Complex ID	New
Molecular description	Engineered Chromosomal Passenger Complex
Complex ID	Jeyaprakash, A.A.,  Klein, U.R.,  Lindner, D.,  Ebert, J.,  Nigg, E.A.,  Conti, E. (2007) Structure of a Survivin-Borealin-INCENP Core Complex Reveals How Chromosomal Passengers Travel Together. Cell (PubMed)
PDB entry	2qfa
Partner	2B
Name	MJ1130 (Kae1-Bud32)
Species	Methanococcus jannaschii
Complex ID	560
Molecular description	Binary sub-complex of the complex KEOPS/EKC
Complex ID	Hecker, A., Lopreiato, R.,  Graille, M.,  Collinet, B.,  Forterre, P.,  Libri, D.,  Van Tilbeurgh, H. Structure of the archaeal Kae1/Bud32 fusion protein MJ1130: a model for the eukaryotic EKC/KEOPS subcomplex. EMBO J. 2008 Aug 7.  (PubMed)
PDB entry	2vwb
Partner	3A
Name	Cdt1-Geminin
Species	H. sapiens
Complex ID	new
Molecular description	Binary complex involved in DNA replication licensing
Complex ID	De Marco V, Gillespie PJ, Li A, Karantzelis N, Christodoulou E, Klompmaker R, van Gerwen S, Fish A, Petoukhov MV, Iliou MS, Lygerou Z, Medema RH, Blow JJ, Svergun DI, Taraviras S, Perrakis A. Quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensing. PNAS, 2009 (PubMed)
PDB entry	2wvr
Partner	5
Name	Xpo-7/tRNA/Ran
Species	S. pombe, S. cerevisiae, synthetic construct
Complex ID	new
Molecular description	Karyopherin nuclear state
Complex ID	Cook AG, Fukuhara N, Jinek M, Conti E. Structures of the tRNA export factor in the nuclear and cytosolic states. Nature. 2009 Sep 3;461(7260):60-5. (PubMed)
PDB entry	3icq
Partner	2BXpo-t-tRNA-Ran
Name	Ndc80
Species	Homo sapiens
Complex ID	254
Molecular description	Bonsai version of the human Ndc80 complex
Complex ID	Ciferri, C.,   Pasqualato, S.,   Screpanti, E.,   Varetti, G.,   Santaguida, S.,   Dos Reis, G.,   Maiolica, A.,   Polka, J.,   De Luca, J.G.,   De Wulf, P.,   Salek, M., Rappsilber, J.,   Moores, C.A.,   Salmon, E.D.,   Musacchio, A. Implications for kinetochore-microtubule attachment from the structure of anengineered Ndc80 complex.(2008) Cell(Cambridge,Mass.) 133: 427-439 (PubMed)
PDB entry	2ve7
Partner	6
Name	Dbp5/RNA/AMPPNP
Species	Homo sapiens
Complex ID	1504
Molecular description	mRNA transport protein Dbp5 in complex with RNA and AMPPNP
Complex ID	von Moeller H, Basquin C, Conti E. The mRNA export protein DBP5 binds RNA and the cytoplasmic nucleoporin NUP214 in a mutually exclusive manner. Nat Struct Mol Biol. 2009 Mar;16(3):247-54.  (PubMed)
PDB entry	3fht
Partner	2B
Name	Dbp5/NUP214
Species	Homo sapiens
Complex ID	1504
Molecular description	mRNA transport protein Dbp5 in complex with Nup214
Complex ID	von Moeller H, Basquin C, Conti E. The mRNA export protein DBP5 binds RNA and the cytoplasmic nucleoporin NUP214 in a mutually exclusive manner. Nat Struct Mol Biol. 2009 Mar;16(3):247-54.  (PubMed)
PDB entry	3fhc
Partner	2B
Name	Importin13/MagoY14
Species	Drosophila melanogaster
Complex ID	FunctionProtein transport
Molecular description
Complex ID	Bono F, Cook AG, Grünwald M, Ebert J, Conti E. Nuclear import mechanism of the EJC component Mago-Y14 revealed by structural studies of importin 13. Mol Cell. 2010 Jan 29;37(2):211-22. (PubMed)
PDB entry	2x1g
Partner	2B
Name	Pex14/Pex19
Species	Homo sapiens
Complex ID	FunctionProtein transport
Molecular description
Complex ID	Neufeld C, Filipp FV, Simon B, Neuhaus A, Schüller N, David C, Kooshapur H, Madl T, Erdmann R, Schliebs W, Wilmanns M, Sattler M. Structural basis for competitive interactions of Pex14 with the import receptors Pex5 and Pex19. EMBO J. 2009 Mar 18;28(6):745-54. (PubMed)
PDB entry	2w85
Partner	16C
Name	Pex14/Pex5
Species	Homo sapiens
Complex ID
Molecular description	Pex14 in complex with the import receptor Pex5
Complex ID	Neufeld C, Filipp FV, Simon B, Neuhaus A, Schüller N, David C, Kooshapur H, Madl T, Erdmann R, Schliebs W, Wilmanns M, Sattler M. Structural basis for competitive interactions of Pex14 with the import receptors Pex5 and Pex19. EMBO J. 2009 Mar 18;28(6):745-54. (PubMed)
PDB entry	2w84
Partner	16C

Single Proteins:

Name	Rrp40
Species
Complex ID	500
Molecular description	Exonuclease belonging to the Exosome complex
Complex ID	Oddone, A.,  Lorentzen, E.,  Basquin, J.,  Gasch, A.,  Rybin, V.,  Conti, E.,  Sattler, M. Structural and Biochemical Characterization of the Yeast Exosome Component Rrp40 EMBO Reports v8 pp.63 , 2007 (PubMed)
PDB entry	2ja9
Partner	16A
Name	Arc1p
Species
Complex ID	243
Molecular description	N-terminal domain of GU4 nucleic-binding protein (export factor)
Complex ID	Simader, H.,  Hothorn, M.,  Suck, D. Structures of the interacting domains from yeast glutamyl-tRNA synthetase and tRNA-aminoacylation and nuclear-export cofactor Arc1p reveal a novel function for an old fold. ACTA D v62 pp.1510-1519 , 2006 (PubMed)
PDB entry	2hqt
Partner	16A
Name	Ynr046w/Tmr12
Species
Complex ID	065
Molecular description	Zinc finger protein from the eRF1 methyltransferase complex
Complex ID	Heurgue-Hamard, V.,  Graille, M.,  Scrima, N.,  Ulryck, N.,  Champ, S.,  Van Tilbeurgh, H.,  Buckingham, R.H. The Zinc Finger Protein Ynr046W is Plurifunctional and a Component of the Erf1 Methyltransferase in Yeast. J.Biol.Chem. v281 pp.36140 , 2006 (PubMed)
PDB entry	2j6a
Partner	3A
Name	Xpo-t
Species
Complex ID	new
Molecular description	Exportin-T, Karyopherin cytosolic state
Complex ID	Cook AG, Fukuhara N, Jinek M, Conti E. Structures of the tRNA export factor in the nuclear and cytosolic states. Nature. 2009 Sep 3;461(7260):60-5. (PubMed)
PDB entry	3ibv
Partner	2BB - Complexes